Pdf ebook: Guide for the Care and Use of Laboratory Animals

Pdf download ebook Guide for the Care and Use of Laboratory Animals

Summary: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideratio

  • Author : N.a
  • Publisher: National Academies Press
  • ISBN: 9780309186636
  • Genre: Science
  • Number of Pages: 246
  • Language: English
  • Views: 1358
  • Downloads: 1358
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Description: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.


Pdf ebook: Fundamentals of Biomechanics

Pdf download ebook Fundamentals of Biomechanics

Summary: Fundamentals of Biomechanics introduces the exciting world of how human movement is created and how it can be improved. Teachers, coaches and physical ther

  • Author : Duane Knudson
  • Publisher: Springer Science & Business Media
  • ISBN: 1475752989
  • Genre: Medical
  • Number of Pages: 337
  • Language: English
  • Views: 1726
  • Downloads: 1726
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Description: Fundamentals of Biomechanics introduces the exciting world of how human movement is created and how it can be improved. Teachers, coaches and physical therapists all use biomechanics to help people improve movement and decrease the risk of injury. The book presents a comprehensive review of the major concepts of biomechanics and summarizes them in nine principles of biomechanics. Fundamentals of Biomechanics concludes by showing how these principles can be used by movement professionals to improve human movement. Specific case studies are presented in physical education, coaching, strength and conditioning, and sports medicine.


Pdf ebook: Botulinum Neurotoxins

Pdf download ebook Botulinum Neurotoxins

Summary: The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but d

  • Author : Andreas Rummel,Thomas Binz
  • Publisher: Springer Science & Business Media
  • ISBN: 3642335705
  • Genre: Medical
  • Number of Pages: 324
  • Language: English
  • Views: 1291
  • Downloads: 1291
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Description: The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.


Pdf ebook: The Psychology of Fake News

Pdf download ebook The Psychology of Fake News

Summary: This volume examines the phenomenon of fake news by bringing together leading experts from different fields within psychology and related areas, and explor

  • Author : Rainer Greifeneder,Mariela Jaffe,Eryn Newman,Norbert Schwarz
  • Publisher: Routledge
  • ISBN: 1000179052
  • Genre: Psychology
  • Number of Pages: 240
  • Language: English
  • Views: 922
  • Downloads: 922
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Description: This volume examines the phenomenon of fake news by bringing together leading experts from different fields within psychology and related areas, and explores what has become a prominent feature of public discourse since the first Brexit referendum and the 2016 US election campaign. Dealing with misinformation is important in many areas of daily life, including politics, the marketplace, health communication, journalism, education, and science. In a general climate where facts and misinformation blur, and are intentionally blurred, this book asks what determines whether people accept and share (mis)information, and what can be done to counter misinformation? All three of these aspects need to be understood in the context of online social networks, which have fundamentally changed the way information is produced, consumed, and transmitted. The contributions within this volume summarize the most up-to-date empirical findings, theories, and applications and discuss cutting-edge ideas and future directions of interventions to counter fake news. Also providing guidance on how to handle misinformation in an age of “alternative facts”, this is a fascinating and vital reading for students and academics in psychology, communication, and political science and for professionals including policy makers and journalists.


Pdf ebook: Endocytosis and Signaling

Pdf download ebook Endocytosis and Signaling

Summary: This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The l

  • Author : Christophe Lamaze,Ian Prior
  • Publisher: Springer
  • ISBN: 3319967045
  • Genre: Science
  • Number of Pages: 329
  • Language: English
  • Views: 1963
  • Downloads: 1963
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Description: This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks’ output. In this book, first a series of reviews describe the endocytic and endosomal system and show how these subcellular platforms sort and regulate a wide range of signaling pathway components and phenotypic outputs. The book then reviews the latest scientific insights into how endocytic trafficking and subcellular location modulate a set of major pathways that are essential to normal cellular function and organisms’ development.


Pdf ebook: Human, All Too Human

Pdf download ebook Human, All Too Human

Summary: German scholar and thinker Friedrich Nietzsche began his career as a linguist and philologist, but over time, his work became increasingly philosophical in

  • Author : Friedrich Nietzsche
  • Publisher: The Floating Press
  • ISBN: 1776527224
  • Genre: Philosophy
  • Number of Pages: 405
  • Language: English
  • Views: 1678
  • Downloads: 1678
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Description: German scholar and thinker Friedrich Nietzsche began his career as a linguist and philologist, but over time, his work became increasingly philosophical in its scope. He came to embrace a radical point of view that prized personal freedom and choice over virtually everything else. In Human, All Too Human, Nietzsche explores the triumphs and tragic shortfalls of human nature in an eminently readable series of aphorisms and short vignettes.


Pdf ebook: Turn On, Tune In, Drop Out

Pdf download ebook Turn On, Tune In, Drop Out

Summary: Written in the psychedelic era, Turn On, Tune In, Drop Out is Timothy Leary at his best, beckoning with humor and irreverence, a vision of individual empow

  • Author : Timothy Leary
  • Publisher: Ronin Publishing
  • ISBN: 1579511058
  • Genre: Body, Mind & Spirit
  • Number of Pages: 160
  • Language: English
  • Views: 711
  • Downloads: 711
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Description: Written in the psychedelic era, Turn On, Tune In, Drop Out is Timothy Leary at his best, beckoning with humor and irreverence, a vision of individual empowerment, personal responsibility, and spiritual awakening. Includes: Start Your Own Religion Education as an Addictive Process Soul Session Buddha as Drop-Out Mad Virgin of Psychedelia God's Secret Agent o Homage to Huxley The Awe-Ful See-Er o The Molecular Revolution MIT is TIM Backwards Neurological Politics "Trickster is a major figure in American Indian folk Wisdom. Also in Sufi Tales … a certain type of "rascal"-with a grin and a wink (and wisdom beyond wisdom) … in the Zen tradition this is known as the School of Crazy Wisdom … Timothy Leary-in his own inimitable way-has become the twentieth century's grand master of crazy wisdom …" - Dr. Jeffrey Mishlove


Pdf ebook: Dietary Reference Intakes for Calcium and Vitamin D

Pdf download ebook Dietary Reference Intakes for Calcium and Vitamin D

Summary: Calcium and vitamin D are essential nutrients for the human body. Establishing the levels of these nutrients that are needed by the North American populati

  • Author : Institute of Medicine,Food and Nutrition Board,Committee to Review Dietary Reference Intakes for Vitamin D and Calcium
  • Publisher: National Academies Press
  • ISBN: 0309212030
  • Genre: Medical
  • Number of Pages: 1132
  • Language: English
  • Views: 830
  • Downloads: 830
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Description: Calcium and vitamin D are essential nutrients for the human body. Establishing the levels of these nutrients that are needed by the North American population is based on the understanding of the health outcomes that calcium and vitamin D affect. It is also important to establish how much of each nutrient may be "too much." Dietary Reference Intakes for Calcium and Vitamin D provides reference intake values for these two nutrients. The report updates the DRI values defined in Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride, the 1997 study from the Institute of Medicine. This 2011 book provides background information on the biological functions of each nutrient, reviews health outcomes that are associated with the intake of calcium and vitamin D, and specifies Estimated Average Requirements and Recommended Dietary Allowances for both. It also identifies Tolerable Upper Intake Levels, which are levels above wish the risk for harm may increase. The book includes an overview of current dietary intake in the U.S. and Canada, and discusses implications of the study. A final chapter provides research recommendations. The DRIs established in this book incorporate current scientific evidence about the roles of vitamin D and calcium in human health and will serve as a valuable guide for a range of stakeholders including dietitians and other health professionals, those who set national nutrition policy, researchers, the food industry, and private and public health organizations and partnerships.


Pdf ebook: Introduction to Swiss Law

Pdf download ebook Introduction to Swiss Law

Summary: What are the origins of direct democracy in Switzerland? How does the Swiss judiciary function? What are the principles of Swiss civil, contract and admini

  • Author : Marc Thommen
  • Publisher: Carl Grossmann Verlag
  • ISBN: 3941159240
  • Genre: Law
  • Number of Pages: 552
  • Language: English
  • Views: 1073
  • Downloads: 1073
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Description: What are the origins of direct democracy in Switzerland? How does the Swiss judiciary function? What are the principles of Swiss civil, contract and administrative law? What is the role of public service broadcasting in the political decision making process? What are the leading cases in tax law? What forms of euthanasia are legal in Switzerland? In this introduction 13 legal scholars of the University of Zürich Law Faculty try to answer these questions and give the reader an overview of Swiss public, private and criminal law. As the first comprehensive introduction to Swiss law in English, it is addressed to both lawyers from abroad and incoming students.


Pdf ebook: Pharmaceuticals, Corporate Crime and Public Health

Pdf download ebook Pharmaceuticals, Corporate Crime and Public Health

Summary: The pharmaceutical industry exists to serve the community, but over the years it has engaged massively in corporate crime, with the public footing the bill

  • Author : Graham Dukes,John Braithwaite,J P Moloney
  • Publisher: Edward Elgar Publishing
  • ISBN: 1783471107
  • Genre: Business & Economics
  • Number of Pages: 424
  • Language: English
  • Views: 1149
  • Downloads: 1149
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Description: The pharmaceutical industry exists to serve the community, but over the years it has engaged massively in corporate crime, with the public footing the bill. This readable study by experts in medicine, law, criminology and public health documents the pr


Pdf ebook: The Discovery of a Visual System

Pdf download ebook The Discovery of a Visual System

Summary:

  • Author : Adrian Horridge
  • Publisher: CABI
  • ISBN: 1789240891
  • Genre: Science
  • Number of Pages: 291
  • Language: English
  • Views: 1666
  • Downloads: 1666
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Description:


Pdf ebook: Global Corruption Report: Sport

Pdf download ebook Global Corruption Report: Sport

Summary: Sport is a global phenomenon engaging billions of people and generating annual revenues of more than US$ 145 billion. Problems in the governance of sports

  • Author : Transparency International
  • Publisher: Routledge
  • ISBN: 1317443756
  • Genre: Business & Economics
  • Number of Pages: 372
  • Language: English
  • Views: 932
  • Downloads: 932
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Description: Sport is a global phenomenon engaging billions of people and generating annual revenues of more than US$ 145 billion. Problems in the governance of sports organisations, fixing of matches and staging of major sporting events have spurred action on many fronts. Yet attempts to stop corruption in sport are still at an early stage. The Global Corruption Report (GCR) on sport is the most comprehensive analysis of sports corruption to date. It consists of more than 60 contributions from leading experts in the fields of corruption and sport, from sports organisations, governments, multilateral institutions, sponsors, athletes, supporters, academia and the wider anti-corruption movement. This GCR provides essential analysis for understanding the corruption risks in sport, focusing on sports governance, the business of sport, planning of major events, and match-fixing. It highlights the significant work that has already been done and presents new approaches to strengthening integrity in sport. In addition to measuring transparency and accountability, the GCR gives priority to participation, from sponsors to athletes to supporters an essential to restoring trust in sport.


Pdf ebook: Yeasts in Natural Ecosystems: Diversity

Pdf download ebook Yeasts in Natural Ecosystems: Diversity

Summary: This book focuses on the diversity of yeasts in aquatic and terrestrial ecosystems, including the association of yeasts with insects, invertebrate and vert

  • Author : Pietro Buzzini,Marc-André Lachance,Andrey Yurkov
  • Publisher: Springer
  • ISBN: 3319626833
  • Genre: Science
  • Number of Pages: 499
  • Language: English
  • Views: 1721
  • Downloads: 1721
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Description: This book focuses on the diversity of yeasts in aquatic and terrestrial ecosystems, including the association of yeasts with insects, invertebrate and vertebrate animals. It offers an overview of the knowledge accumulated in the course of more than 60 years of research and is closely connected with the volume Yeasts in Natural Ecosystems: Ecology by the same editors. In view of the rapid decline of many natural habitats due to anthropogenic activities and climate change, the need to study biodiversity is pressing. Rising temperatures threaten species inhabiting cold and aquatic environments, and species in terrestrial ecosystems are endangered by habitat fragmentation or loss. Most of our knowledge of intrinsic properties (autoecology) of yeasts reported throughout this book is derived from laboratory experiments with pure cultures. Accordingly, the importance of culture collections for ecological studies is highlighted by presenting an overview of worldwide available yeast strains and their origins. All of the chapters were written by leading international yeast research experts, and will appeal to researchers and advanced students in the field of microbial diversity.


Pdf ebook: Strange Blood

Pdf download ebook Strange Blood

Summary: In the mid-1870s, the experimental therapy of lamb blood transfusion spread like an epidemic across Europe and the USA. Doctors tried it as a cure for tube

  • Author : Boel Berner
  • Publisher: transcript Verlag
  • ISBN: 3839451639
  • Genre: History
  • Number of Pages: 216
  • Language: English
  • Views: 1928
  • Downloads: 1928
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Description: In the mid-1870s, the experimental therapy of lamb blood transfusion spread like an epidemic across Europe and the USA. Doctors tried it as a cure for tuberculosis, pellagra and anemia; proposed it as a means to reanimate seemingly dead soldiers on the battlefield. It was a contested therapy because it meant crossing boundaries and challenging taboos. Was the transfusion of lamb blood into desperately sick humans really defensible? The book takes the reader on a journey into hospital wards and lunatic asylums, physiological laboratories and 19th century wars. It presents a fascinating story of medical knowledge, ambitions and concerns - a story that provides lessons for current debates on the morality of medical experimentation and care.


Pdf ebook: The Psychosomatic Assessment

Pdf download ebook The Psychosomatic Assessment

Summary: Psychosomatic medicine has developed methods to increase diagnostic accuracy and improve targeted therapeutic approaches in all fields of medicine. In this

  • Author : G.A. Fava,N. Sonino,T.N. Wise
  • Publisher: Karger Medical and Scientific Publishers
  • ISBN: 3805598548
  • Genre: Medical
  • Number of Pages: 254
  • Language: English
  • Views: 1130
  • Downloads: 1130
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Description: Psychosomatic medicine has developed methods to increase diagnostic accuracy and improve targeted therapeutic approaches in all fields of medicine. In this context, clinimetrics, the science of clinical measurements, provides unprecedented opportunities for psychosomatic assessment.This volume illustrates how this approach can be translated into everyday practice complementing and improving the medical interview. The most sensitive and reliable clinical methods are presented for evaluating specific psychosocial aspects of disease, i.e. childhood adversities, life events and chronic stress, lifestyle, sexual function, subclinical and affective disturbances, personality, illness behavior, well-being and family dynamics. Each chapter provides practical illustrations as to how crucial information can be obtained with specific methods individualized according to the patients’ needs. A hyperlink is provided to a website that contains many of the instruments assessed in the volume.This book enables the reader to understand the value of the psychosomatic approach in clinical practice. It is intended to expand and refine the skills of clinicians who work in general and specialized medicine and psychiatry, whether physicians, psychologists or other health professionals.


Pdf ebook: Liver Regeneration and Carcinogenesis

Pdf download ebook Liver Regeneration and Carcinogenesis

Summary: Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used ex

  • Author : Gerard Meurant
  • Publisher: Elsevier
  • ISBN: 9780080535548
  • Genre: Science
  • Number of Pages: 402
  • Language: English
  • Views: 1184
  • Downloads: 1184
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Description: Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level


Pdf ebook: Brain and Culture

Pdf download ebook Brain and Culture

Summary: Research shows that between birth and early adulthood the brain requires sensory stimulation to develop physically. The nature of the stimulation shapes th

  • Author : Bruce E. Wexler
  • Publisher: MIT Press
  • ISBN: 0262265141
  • Genre: Science
  • Number of Pages: 320
  • Language: English
  • Views: 1243
  • Downloads: 1243
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Description: Research shows that between birth and early adulthood the brain requires sensory stimulation to develop physically. The nature of the stimulation shapes the connections among neurons that create the neuronal networks necessary for thought and behavior. By changing the cultural environment, each generation shapes the brains of the next. By early adulthood, the neuroplasticity of the brain is greatly reduced, and this leads to a fundamental shift in the relationship between the individual and the environment: during the first part of life, the brain and mind shape themselves to the major recurring features of their environment; by early adulthood, the individual attempts to make the environment conform to the established internal structures of the brain and mind. In Brain and Culture, Bruce Wexler explores the social implications of the close and changing neurobiological relationship between the individual and the environment, with particular attention to the difficulties individuals face in adulthood when the environment changes beyond their ability to maintain the fit between existing internal structure and external reality. These difficulties are evident in bereavement, the meeting of different cultures, the experience of immigrants (in which children of immigrant families are more successful than their parents at the necessary internal transformations), and the phenomenon of interethnic violence. Integrating recent neurobiological research with major experimental findings in cognitive and developmental psychology—with illuminating references to psychoanalysis, literature, anthropology, history, and politics—Wexler presents a wealth of detail to support his arguments. The groundbreaking connections he makes allow for reconceptualization of the effect of cultural change on the brain and provide a new biological base from which to consider such social issues as "culture wars" and ethnic violence.